Human Blood Group RhD Polypeptide (RHD) Protein
494€ (100 µg)
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Name
Human Blood Group RhD Polypeptide (RHD) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx651012
Tested Applications
WB, SDS-PAGE
Description
Human RHD Protein is a recombinant Human protein. It is produced in a Prokaryotic expression system (E. coli).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Blood Group RhD Polypeptide (RHD) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Asp35-Ser75 + His260-Pro291 Tag: N-terminal His and SUMO tags |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 20.12 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Availability | Shipped within 7-15 working days. |
| Storage | Aliquot and store at -20 °C to 80°C. Avoid repeated freeze-thaw cycles. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q02161 |
| Gene ID | 6007 |
| OMIM | 111680 |
| Alias | Blood group Rh(D) polypeptide,RH,Rh4,RH30,RhII,RhPI,DIIIc,RHCED,RHDel,RHPII,RhDCw,CD240D,Rh polypeptide 2,Rhesus D antigen |
| Background | Protein RHD |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile ddH2O. Do not vortex. Concentration: Prior to lyophilization: 1.06 mg/ml |
Background
RHD (Rh blood group D antigen), encoded by the RHD gene, is a major component of the Rh blood group system, one of the most clinically significant blood group systems in humans. The Rh system includes a range of antigens, but the D antigen is the most important for its role in blood transfusion compatibility, pregnancy, and disease. The Rh system is widely recognized in transfusion medicine, where the presence or absence of the D antigen determines whether an individual is classified as Rh-positive (Rh+) or Rh-negative (Rh-). The Rh system, particularly the D antigen, plays a crucial role in immune reactions, alloimmunization, and hemolytic disease of the newborn (HDN). The RHD gene is located on chromosome 1 and is closely linked to the RHCE gene, which encodes other Rh antigens, particularly C and E. The Rh proteins, including the D antigen, are integral membrane proteins that span the cell membrane and play an essential role in the transportation of ions and gases across the cell membrane, especially in erythrocytes (red blood cells). The RHD gene codes for the RhD protein, and its expression is key to determining whether an individual expresses the RhD antigen on the surface of their erythrocytes.
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