Human Receptor Tyrosine Kinase Like Orphan Receptor 2 (ROR2) Protein
234€ (10 µg)
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Name
Human Receptor Tyrosine Kinase Like Orphan Receptor 2 (ROR2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx168249
Tested Applications
WB, SDS-PAGE
Description
Human Receptor Tyrosine Kinase Like Orphan Receptor 2 Protein is a recombinant Human protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Receptor Tyrosine Kinase Like Orphan Receptor 2 (ROR2) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Trp683-Val934 Tag: N-terminal His and GST tags |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 57.6 kDa Observed MW: 58 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | BDB,BDB1,NTRKR2,Neurotrophic tyrosine kinase, receptor-related 2,Tyrosine-protein kinase transmembrane receptor ROR2 |
| Background | Protein ROR2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2) is closely related to ROR1 but has distinct functions, particularly in skeletal and cardiovascular development. ROR2 acts as a coreceptor for Wnt5a in the planar cell polarity pathway, essential for cell movement and polarity during embryogenesis. Mutations in the ROR2 gene have been associated with Robinow syndrome and brachydactyly type B, which are developmental disorders affecting skeletal and facial structures. ROR2 is also implicated in cancer biology, where its expression correlates with aggressive tumor behaviors, including invasion and metastasis. Its dual roles in development and disease make ROR2 a critical player in both developmental biology and oncology research.
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