Human Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Protein
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935106861
info@markelab.com
Precio
212.5€ (10 µg)
Protein ROR1
proveedor
Abbexareference
abx068836Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) is a recombinant Human protein produced in E. coli using Prokaryotic expression.
Background
ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1) is a member of the receptor tyrosine kinase family, playing a pivotal role in embryonic development and cellular signaling. While minimally expressed in normal adult tissues, ROR1 is highly expressed in various cancers, including chronic lymphocytic leukemia and breast cancer, where it contributes to tumor progression, survival, and metastasis. This makes ROR1 a promising therapeutic target in oncology. The receptor participates in Wnt5a-mediated non-canonical Wnt signaling pathways, which regulate cell migration and cytoskeletal dynamics, critical processes during development and pathological states such as cancer. Its restricted expression pattern in normal tissues highlights its potential for targeted cancer therapies.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ROR1
dry ice
No
availability
Shipped within 5-7 working days.
alias
NTRKR1,dJ537F10.1,Inactive tyrosine-protein kinase transmembrane receptor ROR1,Neurotrophic tyrosine kinase, receptor-related 1
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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