Human Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) CLIA Kit
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Description
Human Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
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Product specifications
| Category | CLIA Kits |
| Immunogen Target | Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.07 ng/ml - 50 ng/ml |
| Sensitivity | < 0.03 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | NTRKR1,dJ537F10.1,Inactive tyrosine-protein kinase transmembrane receptor ROR1,Neurotrophic tyrosine kinase, receptor-related 1 |
| Background | CLIA Kits ROR1 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1) is a member of the receptor tyrosine kinase family, playing a pivotal role in embryonic development and cellular signaling. While minimally expressed in normal adult tissues, ROR1 is highly expressed in various cancers, including chronic lymphocytic leukemia and breast cancer, where it contributes to tumor progression, survival, and metastasis. This makes ROR1 a promising therapeutic target in oncology. The receptor participates in Wnt5a-mediated non-canonical Wnt signaling pathways, which regulate cell migration and cytoskeletal dynamics, critical processes during development and pathological states such as cancer. Its restricted expression pattern in normal tissues highlights its potential for targeted cancer therapies.
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