Human PYM Homolog 1 Exon Junction Complex-Associated Factor (WIBG) Protein
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Human Partner of Y14 and Mago Protein is a recombinant protein from Human produced in E. coli. Recombinant Human Partner of Y14 and Mago is produced by our E.coli expression system and the target gene encoding Met1-Leu204 is expressed with a 6His tag at the C-terminus.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Partner of Y14 and Mago |
| Host | E. coli |
| Origin | Human |
| Observed MW | Molecular Weight: 23.7 kDa Sequence Fragment: Met1-Leu204 Tag: C-terminal 6 His tag Validity: The validity for this protein is 6 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at < -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BRP8 |
| Background | Protein WIBG |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Related Products
PYM Homolog 1 Exon Junction Complex-Associated Factor (WIBG) Antibody
Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA; the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC.
Ver Producto
Human PYM Homolog 1 Exon Junction Complex-Associated Factor (WIBG) Protein
Human Partner of Y14 and Mago Protein is a recombinant protein from Human produced in E. coli. Recombinant Human Partner of Y14 and Mago is produced by our E.coli expression system and the target gene encoding Met1-Leu204 is expressed with a 6His tag at the C-terminus.
Ver Producto