Human Protein C Inhibitor (SERPINA5) Protein
221€ (10 µg)
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name
Human Protein C Inhibitor (SERPINA5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166246
tested applications
WB, SDS-PAGE
Description
Protein C Inhibitor (SERPINA5) is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Protein C Inhibitor (SERPINA5) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 44.7 kDa Observed MW (SDS-PAGE): 45 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser43-Pro406 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | PCI,PAI3,PAI-3; PCI-B,PROCI,PLANH3,Plasma serine protease inhibitor,Plasminogen activator inhibitor 3,Protein C inhibitor,Serpin A5 Acrosomal serine protease inhibitor |
| Background | Protein SERPINA5 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SERPINA5, also known as protein C inhibitor (PCI), is a member of the serpin (serine protease inhibitor) superfamily. This gene encodes a protein that plays a crucial role in the regulation of proteolytic processes, particularly those involved in the coagulation and fibrinolysis pathways. Located on chromosome 14q32.13, the SERPINA5 gene is part of the SERPIN family, which is characterized by its ability to inhibit serine proteases through a conserved reactive center loop (RCL) mechanism. SERPINA5 is primarily expressed in the liver, but it is also found in a wide range of tissues, including the kidney, testis, and seminal plasma. The protein encoded by SERPINA5 is involved in the inhibition of several key proteases, including activated protein C, which plays a critical role in the regulation of blood coagulation
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