Human Prominin 1 (PROM1) Protein
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935106861
info@markelab.com
Precio
273€ (10 µg)
Protein PROM1
proveedor
Abbexareference
abx167182Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
PROM1 Protein is a recombinant Human protein expressed in E. coli.
Background
Prominin-1 (PROM1), also known as CD133, is a transmembrane glycoprotein that plays a significant role in stem cell biology and cellular development. Widely recognized as a marker for stem and progenitor cells in various tissues, PROM1 is expressed on the apical surface of epithelial and hematopoietic stem cells. It participates in cellular differentiation and is crucial for maintaining the stem cell niche, with implications in tissue regeneration and repair. PROM1 has become a focus of research due to its role in cell signaling and its involvement in numerous developmental pathways, including those of the nervous system, retina, and digestive tract. Additionally, aberrant PROM1 expression is associated with cancer, specifically in cancer stem cells, and its presence is often used as a marker to identify cells with tumorigenic potential. PROM1’s relevance to cellular organization and tissue homeostasis, along with its association with pathological conditions, makes it an important molecule in cell biology and oncology.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Prominin 1 (PROM1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 30.5 kDa Observed MW (SDS-PAGE): 28 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ile171-Asp431 Tag: N-terminal His tag
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
PROM1
dry ice
No
availability
Shipped within 5-7 working days.
alias
RP41,AC133,CD133,MCDR2,STGD4,CORD12,PROML1,MSTP061,Prominin-like protein 1
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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