Human Pro-Opiomelanocortin (POMC) Protein
221€ (10 µg)
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935106861
info@markelab.com
name
Human Pro-Opiomelanocortin (POMC) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068696
tested applications
WB, SDS-PAGE
Description
Human Adrenocorticotropic Hormone is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Pro-Opiomelanocortin (POMC) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 30.9 kDa Observed MW (SDS-PAGE): 37 kDa Possible reasons why the actual band size differs from the predicted band size: 1. Splice variants. Alternative splicing may create different sized proteins from the same gene. 2. Relative charge. The composition of amino acids may affect the charge of the protein. 3. Post-translational modification. Phosphorylation, glycoslyation, methylation etc. may affect the band size. 4. Post-translational cleavage. Many proteins are synthesised as pro-proteins, and then cleaved to give the active form. 5. Polymerisation of the target protein. Dimerisation, multimerisation etc. will increase the band size observed. Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu23-Glu267 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01189 |
| Gene ID | 5443 |
| Alias | LPH,MSH,NPP,POC,ACTH,CLIP,OBAIRH,Corticotropin,lipotropin |
| Background | Protein POMC |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Proopiomelanocortin (POMC) is a large precursor polypeptide produced primarily in the anterior pituitary gland, but also in the hypothalamus, skin, and other tissues. POMC undergoes extensive post-translational processing to produce multiple biologically active peptides, including adrenocorticotropic hormone (ACTH), melanocyte-stimulating hormones (MSH), and beta-endorphin. These peptides have diverse roles in regulating physiological processes such as stress response, immune function, energy homeostasis, and pigmentation.
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