Human Poliovirus Receptor Related Protein 4 / PVRL4 (NECTIN4) CLIA Kit
845€ (96 tests)
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935106861
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name
Human Poliovirus Receptor Related Protein 4 / PVRL4 (NECTIN4) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx493884
tested applications
CLIA
Description
Human Poliovirus Receptor Related Protein 4 (PVRL4) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Poliovirus Receptor Related Protein 4 / PVRL4 (NECTIN4) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 125 pg/ml - 8000 pg/ml |
| Sensitivity | < 51 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | LNIR,PRR4,EDSS1,PVRL4,nectin-4,Ig superfamily receptor LNIR,Nectin cell adhesion molecule 4,Poliovirus receptor-related protein 4 |
| Background | CLIA Kits NECTIN4 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nectin cell adhesion molecule 4 (NECTIN4) is highly expressed in epithelial tissues and has emerged as a significant player in cancer biology. Its overexpression is linked to the progression of aggressive cancers, including breast and urothelial carcinomas. NECTIN4 promotes tumor growth and metastasis by activating key signaling pathways such as PI3K/AKT and MAPK, which drive cell proliferation, survival, and migration. Its expression has also been associated with poor clinical outcomes, making it a potential biomarker and therapeutic target for cancer treatment strategies.
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