Human Poliovirus Receptor (PVR) ELISA Kit
689€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Poliovirus Receptor (PVR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx585772
tested applications
ELISA
Description
Human Poliovirus Receptor (PVR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Poliovirus Receptor (PVR) concentrations in tissue homogenates, cell lysates and other biological fluids.. This assay has high sensitivity and excellent specificity for detection of Poliovirus Receptor (PVR)
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Poliovirus Receptor (PVR) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | Poliovirus receptor,PVS,HVED,CD155,NECL5,TAGE4,Necl-5,Nectin-like protein 5 |
| Background | Elisa kits for PVR |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PVR, also known as CD155, is a cell adhesion molecule primarily involved in cell signaling, immune modulation, and viral entry. The gene encoding this protein is found on chromosome 19q13.31, and the protein was initially identified as the receptor for poliovirus, facilitating viral entry into cells. However, PVR is not limited to viral entry functions; it plays a significant role in immune cell interactions, migration, and tissue development. Structurally part of the immunoglobulin superfamily, PVR is widely expressed in various tissues, including epithelial cells, endothelial cells, and immune cells, and is upregulated in certain cancers, suggesting an adaptive role in tumor immune escape mechanisms. This protein is a primary ligand for several immune checkpoints such as DNAM-1 (CD226), TIGIT, and CD96, highlighting its importance in immune system modulation.
