Human Platelet glycoprotein Ib beta chain (GP1BB) ELISA Kit
715€ (96 tests)
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name
Human Platelet glycoprotein Ib beta chain (GP1BB) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525879
tested applications
ELISA
Description
Human Platelet glycoprotein Ib beta chain (GP1BB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Platelet glycoprotein Ib beta chain (GP1BB) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Platelet glycoprotein Ib beta chain (GP1BB) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P13224 |
| Gene ID | 2812 |
| Alias | BS,CD42C,GPIBB,BDPLT1,GPIbbeta,Platelet glycoprotein Ib beta chain, GP-Ib beta,GPIb-beta,GPIbB,Antigen CD42b-beta,CD42c |
| Background | Elisa kits for GP1BB |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Glycoprotein Ib platelet subunit beta (GP1BB) is a critical component of the Glycoprotein Ib-IX-V (GPIb-IX-V) complex, a receptor complex expressed on the surface of platelets. This receptor is central to platelet adhesion under conditions of high shear stress and plays a pivotal role in the initiation of platelet plug formation, particularly in arterial circulation where rapid blood flow is present. The GPIb-IX-V complex interacts with von Willebrand factor (vWF) to mediate the tethering of platelets to the site of vascular injury, marking the beginning of the hemostatic process that leads to clot formation and wound healing. GP1BB is the beta subunit of the GPIb-IX-V complex, and it is necessary for proper assembly and function of the entire receptor complex. The GP1BB protein contributes to the stability of the receptor on the platelet surface and forms part of the binding interface with other components of the GPIb-IX-V complex, including GP1BA, GPIX, and GPV.
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