Human Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) CLIA Kit

Este producto es parte de PDGFR - platelet derived growth factor receptor
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845€ (96 tests)

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935106861
info@markelab.com
name
Human Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx190202
tested applications
CLIA

Description

Human Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryCLIA Kits
Immunogen TargetPlatelet Derived Growth Factor Receptor Like Protein (PDGFRL)
ReactivityHuman
Detection MethodChemiluminescent
Assay DataQuantitative
Assay TypeSandwich
Test Range13.7 pg/ml - 10000 pg/ml
Sensitivity< 6.5 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsCLIA
Sample TypeSerum, plasma and other biological fluids.
AvailabilityShipped within 5-7 working days.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasPDGRL,PRLTS,PDGF receptor beta-like tumor suppressor,PDGFR-like protein
BackgroundCLIA Kits PDGFRL
StatusRUO
NoteThe validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Platelet derived growth factor receptor like (PDGFRL) lacks intrinsic kinase activity and is thought to function in the regulation of extracellular matrix components and intercellular communication although its precise role is less defined compared to PDGFRA and PDGFRB mutations in PDGFRL have been linked to tumor suppressor activity in colorectal and gastric cancers suggesting it may act as a modulator of growth factor signaling networks its reduced expression has been correlated with increased tumor invasiveness and metastasis in some cancers indicating its potential importance in maintaining cellular homeostasis ongoing research seeks to clarify its role in cellular signaling and its impact on cancer progression and therapeutic resistance.

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