Human Platelet Derived Growth Factor Receptor Beta (PDGFRB) ELISA Kit
585€ (96 tests)
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Name
Human Platelet Derived Growth Factor Receptor Beta (PDGFRB) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx358296
Tested Applications
ELISA
Description
Human Platelet Derived Growth Factor Receptor Beta (PDGFRB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Platelet Derived Growth Factor Receptor Beta (PDGFRB) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Platelet Derived Growth Factor Receptor Beta (PDGFRB) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | 0.1 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P09619 |
| Alias | IMF1,KOGS,IBGC4,JTK12,PDGFR,PENTT,CD140B,PDGFR1,PDGFR-1,CD140 antigen-like family member B,Platelet-derived growth factor receptor 1,Beta-type platelet-derived growth factor receptor,PDGF-R-beta,PDGFR-beta |
| Background | Elisa Kits for: PDGFRB |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
Platelet derived growth factor receptor beta (PDGFRB) similarly functions as a receptor for PDGFs and is crucial for vascular development and the regulation of blood vessel maturation and stability PDGFRB is expressed in pericytes and vascular smooth muscle cells, where it modulates cell migration, proliferation, and differentiation its activation is pivotal in angiogenesis and vascular remodeling through downstream signaling pathways including STAT3 and Ras-MAPK aberrations in PDGFRB signaling are implicated in pathologies such as proliferative retinopathies, atherosclerosis, and certain myeloproliferative disorders including chronic eosinophilic leukemia targeted inhibitors have been developed to counteract PDGFRB-driven malignancies while new studies focus on its contribution to immune modulation and tissue regeneration.
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