Human Phosphodiesterase 9A (PDE9A) Protein

Product Graph
1235€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Phosphodiesterase 9A (PDE9A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693526
tested applications
SDS-PAGE

Description

Human PDE9A Protein is a recombinant protein from Human produced in Baculovirus-Insect Cells. A DNA sequence encoding the full length of human PDE9A (O76083-2) (Met 1-Ala 533) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Phosphodiesterase 9A (PDE9A)
Host
Insect
Origin
Human
Observed MW
Molecular Weight: 89.5 kDa

Sequence Fragment: Met1-Ala533

Tag: N-terminal His tag and GST tag

Validity: The validity for this protein is 12 months.
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
100 µg
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile 20mM Tris, 500mM NaCl, 5mM GSH, pH 7.4, 10% gly.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O76083-2
Background
Protein PDE9A
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Related Products
EH10983
Human PDE9A (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) ELISA Kit
Ver Producto
FNab06263
PDE9A antibody
Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP(PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart(PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein(Probable). In brain, involved in cognitive function, such as learning and long-term memory(By similarity).
Ver Producto
abx236263
Phosphodiesterase 9A (PDE9A) Antibody
PDE9A Antibody is a Rabbit Polyclonal against PDE9A.
Ver Producto