Human PHD Finger Protein 7 (PHF7) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PHF7
proveedor
Abbexareference
abx538673Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human PHD Finger Protein 7 (PHF7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PHD Finger Protein 7 (PHF7) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PHF7 is a histone-binding protein containing a PHD finger domain that recognizes methylated histones, particularly H3K4me3, to regulate transcriptional activation. PHF7 plays a role in spermatogenesis and male fertility by coordinating chromatin remodeling and gene expression during germ cell development. It interacts with transcriptional regulators and chromatin modifiers to activate genes essential for germ cell differentiation and meiosis. PHF7 is specifically expressed in testicular tissues, where it facilitates proper gene expression programs for spermatocyte maturation. Dysregulation or mutations in PHF7 are associated with male infertility due to disrupted spermatogenesis and impaired germ cell differentiation. Knockdown studies reveal defective chromatin remodeling, reduced germ cell proliferation, and meiotic arrest, emphasizing its role in transcriptional activation, germline development, and reproductive health.
Características del producto
category
ELISA Kits
immunogen target
PHD Finger Protein 7 (PHF7)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
HSPC045, HSPC226, NYD-SP6,Testis development protein NYD-SP6
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PHF7
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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