Human Peroxisome Proliferator-Acivated Receptor Gamma (PPAR-g) Protein

Este producto es parte de PPAR - peroxisome proliferator activated receptor
Product Graph
351€ (10 µg)

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935106861
info@markelab.com
name
Human Peroxisome Proliferator-Acivated Receptor Gamma (PPAR-g) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx682061
tested applications
SDS-PAGE

Description

Human Peroxisome Proliferator-Acivated Receptor Gamma (PPAR-g) Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Peroxisome Proliferator-Acivated Receptor Gamma (PPAR-g)
Host
E. coli
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Origin
Human
Conjugation
Unconjugated
Expression
Recombinant
Size 1
10 µg
Size 2
100 µg
Size 3
1 mg
Form
Liquid 
Tested Applications
SDS-PAGE
Availability
Shipped within 10-20 working days.
Storage
Aliquot and store at -20 °C.
Dry Ice
No
UniProt ID
P37231
Alias
GLM1,CIMT1,NR1C3,PPARG1,PPARG2,PPARG5,PPARgamma,Nuclear receptor subfamily 1 group C member 3
Background
Protein PPARG
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Peroxisome proliferator activated receptor gamma (PPARG) is a nuclear receptor that plays a central role in the regulation of glucose and lipid metabolism, adipogenesis, and inflammation PPARG is highly expressed in adipose tissue, where it regulates the differentiation of preadipocytes into mature adipocytes and controls the storage of fatty acids PPARG also modulates the expression of genes involved in insulin sensitivity, glucose homeostasis, and lipid storage, and it is a critical factor in maintaining metabolic balance Dysregulation of PPARG has been associated with a variety of metabolic disorders, including type 2 diabetes, obesity, and cardiovascular disease PPARG is a major target for drugs like thiazolidinediones (TZDs), which are used to improve insulin sensitivity in type 2 diabetes However, PPARG activation also influences immune responses and inflammation, and its role in chronic inflammation has linked it to diseases such as atherosclerosis and cancer Modulating PPARG activity offers therapeutic potential for addressing metabolic diseases, inflammatory conditions, and cancer, making it an important target for drug development in multiple areas of medicine

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