Human PECAM-1 (Platelet/Endothelial Cell Adhesion Molecule 1) ELISA Kit

Este producto es parte de PECAM1 - platelet and endothelial cell adhesion molecule 1
Human PECAM-1 (Platelet/Endothelial Cell Adhesion Molecule 1) ELISA Kit
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Name
Human PECAM-1 (Platelet/Endothelial Cell Adhesion Molecule 1) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH0021
Tested Applications
ELISA

Documentos del producto

Instrucciones
Descargar
Data sheet

Especificaciones del producto

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.781-50ng/ml
Sensitivity
0.469ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P16284
Alias
CD31,PECA1,PECAM-1,endoCAM,CD31/EndoCAM,Platelet endothelial cell adhesion molecule,GPIIA'
Background
Elisa kits for PECAM1
Status
RUO

Background

PECAM1 (Platelet and Endothelial Cell Adhesion Molecule 1), also known as CD31, is an integral member of the immunoglobulin (Ig) superfamily and functions primarily as a cell adhesion molecule. It plays critical roles in various physiological and pathological processes, including leukocyte transmigration, angiogenesis, vascular integrity, and immune response regulation. PECAM-1 is highly expressed on the surface of endothelial cells lining blood vessels, platelets, monocytes, neutrophils, and some subsets of T cells. Its pivotal role in mediating cell-cell interactions makes it central to maintaining vascular homeostasis and coordinating immune responses. PECAM-1 is widely recognized for its involvement in processes like leukocyte extravasation, where it facilitates the migration of immune cells across the endothelium during inflammation. Additionally, it serves as an essential player in maintaining the structural integrity of the vascular endothelium and modulating signaling pathways linked to cell survival and inflammation. Given its broad expression and functional diversity, PECAM-1 has been a focal point of research in vascular biology, inflammation, and cardiovascular diseases.

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