Human Paired Box Gene 9 (PAX9) Protein
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Pida mas información
935106861
info@markelab.com
Precio
234€ (10 µg)
Protein PAX9
proveedor
Abbexareference
abx650734Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human PAX9 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
PAX9 is a transcription factor critical for embryonic development, particularly in skeletal and craniofacial formation, tooth development, and pharyngeal arch patterning. It regulates the expression of genes essential for tooth morphogenesis, including odontogenesis, ensuring the correct formation of dental structures such as molars and incisors. Mutations in PAX9 lead to oligodontia, a condition characterized by the congenital absence of multiple teeth, and are also associated with cleft palate and jaw malformations. PAX9 interacts with other transcription factors like MSX1 to coordinate craniofacial and dental development. In knockout models, PAX9 deficiency results in arrested tooth development, defective craniofacial structures, and impaired skeletal patterning. Its essential role in epithelial-mesenchymal interactions during organogenesis underscores its importance in tissue-specific development, tooth regeneration, and congenital anomalies.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Paired Box Gene 9 (PAX9)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 40.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Leu341 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
PAX9
dry ice
No
availability
Shipped within 5-7 working days.
alias
STHAG3
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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