Human P-Selectin Glycoprotein Ligand 1 (SELPLG) Protein
1118€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human P-Selectin Glycoprotein Ligand 1 (SELPLG) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx692607
Tested Applications
SDS-PAGE
Description
Human PSGL-1 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the extracellular domain (Met1-Val295) of human PSGL-1 precursor (AAC50061.1) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | PSGL-1 |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Val295 Tag: C-terminal His tag and Fc tag |
| Origin | Human |
| Observed MW | 57.1 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | AAC50061.1 |
| Alias | P-selectin glycoprotein ligand 1,CLA,CD162,PSGL1,PSGL-1,Selectin P ligand |
| Background | Protein SELPLG |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Background
Selectin P ligand (SELPLG), also known as CD162 or P-selectin glycoprotein ligand-1 (PSGL-1), is a critical adhesion molecule that mediates interactions between leukocytes and endothelial cells. Encoded by the SELPLG gene on chromosome 12 in humans, SELPLG plays an essential role in the immune response by facilitating leukocyte tethering and rolling on the endothelium during inflammation and immune surveillance. This glycoprotein ligand interacts with selectins, specifically P-, E-, and L-selectins, which are expressed on activated endothelial cells and platelets, to initiate leukocyte adhesion at inflammation sites. SELPLG's ability to engage in interactions with multiple selectins allows it to participate in a variety of immune functions, from neutrophil recruitment to lymphocyte homing and trafficking. This glycoprotein ligand is particularly important in pathological conditions where leukocyte migration into tissues is crucial, such as infection, inflammation, and tissue injury.
Productos relacionados
P-Selectin Glycoprotein Ligand 1 (SELPLG) Antibody
P-Selectin Glycoprotein Ligand 1 Antibody is a Rabbit Polyclonal against P-Selectin Glycoprotein Ligand 1.…
Ver producto
P-Selectin Glycoprotein Ligand 1 (SELPLG) Antibody
CD162 Antibody is a Mouse Monoclonal against CD162.…
Ver producto
P-Selectin Glycoprotein Ligand 1 (SELPLG) Antibody (PE)
CD162 Antibody is a Mouse Monoclonal against CD162.…
Ver producto