935106861
info@markelab.com
Precio
687.5€ (96 tests)
Human P-Selectin Glycoprotein Ligand 1 (SELPLG) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human P-Selectin Glycoprotein Ligand 1 (SELPLG) concentrations in tissue homogenates, cell lysates and other biological fluids.
Selectin P ligand (SELPLG), also known as CD162 or P-selectin glycoprotein ligand-1 (PSGL-1), is a critical adhesion molecule that mediates interactions between leukocytes and endothelial cells. Encoded by the SELPLG gene on chromosome 12 in humans, SELPLG plays an essential role in the immune response by facilitating leukocyte tethering and rolling on the endothelium during inflammation and immune surveillance. This glycoprotein ligand interacts with selectins, specifically P-, E-, and L-selectins, which are expressed on activated endothelial cells and platelets, to initiate leukocyte adhesion at inflammation sites. SELPLG's ability to engage in interactions with multiple selectins allows it to participate in a variety of immune functions, from neutrophil recruitment to lymphocyte homing and trafficking. This glycoprotein ligand is particularly important in pathological conditions where leukocyte migration into tissues is crucial, such as infection, inflammation, and tissue injury.
ELISA Kits
P-Selectin Glycoprotein Ligand 1 (SELPLG)
Human
0.313 ng/ml - 20 ng/ml
< 0.188 ng/ml
Sandwich
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
P-selectin glycoprotein ligand 1,CLA,CD162,PSGL1,PSGL-1,Selectin P ligand
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
SELPLG
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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