Human P-Selectin Glycoprotein Ligand 1 (SELPLG) ELISA Kit
643.5€ (96 tests)
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name
Human P-Selectin Glycoprotein Ligand 1 (SELPLG) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx156688
tested applications
ELISA
Description
Human P-Selectin Glycoprotein Ligand 1 (SELPLG) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human P-Selectin Glycoprotein Ligand 1 (SELPLG) concentrations in serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | P-Selectin Glycoprotein Ligand 1 (SELPLG) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.625 ng/ml - 40 ng/ml |
| Sensitivity | < 0.26 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q14242 |
| Gene ID | 6404 |
| Alias | P-selectin glycoprotein ligand 1,CLA,CD162,PSGL1,PSGL-1,Selectin P ligand |
| Background | Elisa Kits for: SELPLG |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Selectin P ligand (SELPLG), also known as CD162 or P-selectin glycoprotein ligand-1 (PSGL-1), is a critical adhesion molecule that mediates interactions between leukocytes and endothelial cells. Encoded by the SELPLG gene on chromosome 12 in humans, SELPLG plays an essential role in the immune response by facilitating leukocyte tethering and rolling on the endothelium during inflammation and immune surveillance. This glycoprotein ligand interacts with selectins, specifically P-, E-, and L-selectins, which are expressed on activated endothelial cells and platelets, to initiate leukocyte adhesion at inflammation sites. SELPLG's ability to engage in interactions with multiple selectins allows it to participate in a variety of immune functions, from neutrophil recruitment to lymphocyte homing and trafficking. This glycoprotein ligand is particularly important in pathological conditions where leukocyte migration into tissues is crucial, such as infection, inflammation, and tissue injury.
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