Human Nucleosome Assembly Protein 1 Like Protein 1 (NAP1L1) Protein
221€ (10 µg)
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935106861
info@markelab.com
name
Human Nucleosome Assembly Protein 1 Like Protein 1 (NAP1L1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650737
tested applications
WB, SDS-PAGE
Description
Human NAP1L1 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Nucleosome Assembly Protein 1 Like Protein 1 (NAP1L1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 37.4 kDa Observed MW (SDS-PAGE): 40 kDa Concentration: Prior to lyophilization: 400 µg/ml Sequence Fragment: Ala2-Thr289 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55209 |
| Alias | NRP,NAP1,NAP1L,NAP-1-related protein,Hnrp |
| Background | Protein NAP1L1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Nucleosome assembly protein 1 like 1 (NAP1L1) is a protein involved in chromatin remodeling and nucleosome assembly, playing an essential role in regulating gene expression and DNA repair NAP1L1 functions by facilitating the assembly of nucleosomes, which are the structural units of chromatin, ensuring that DNA is packaged efficiently into the nucleus while remaining accessible for transcription and replication The protein interacts with histones and other chromatin components to assemble and disassemble nucleosomes, enabling the dynamic regulation of gene expression in response to cellular needs NAP1L1 is involved in maintaining genomic stability, as proper nucleosome assembly is crucial for DNA repair and the prevention of DNA damage Dysregulation of NAP1L1 expression or function can lead to various diseases, including cancers and developmental disorders, where faulty chromatin assembly and gene regulation contribute to tumor progression or developmental abnormalities In addition, NAP1L1 is implicated in the regulation of cell cycle progression, influencing cell division and differentiation processes Its role in chromatin dynamics, gene regulation, and DNA repair underscores its importance in maintaining normal cellular function and preventing disease
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