Human Neuroplastin (NPTN) Protein
1872€ (1 mg)
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name
Human Neuroplastin (NPTN) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx654543
tested applications
WB, SDS-PAGE
Description
Human Neuroplastin (NPTN) Protein is a Recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Neuroplastin (NPTN) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 1-2 months. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y639 |
| Gene ID | 27020 |
| OMIM | 612820 |
| Alias | GP55,GP65,SDR1,np55,np65,SDFR1, Stromal cell-derived receptor 1 |
| Background | Protein NPTN |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Neuroplastin (NPTN) is a member of the immunoglobulin superfamily and plays a crucial role in synaptic plasticity, learning, and memory. The NPTN gene is located on chromosome 15q24 and encodes two main isoforms through alternative splicing: Neuroplastin-55 (Np55) and Neuroplastin-65 (Np65). These isoforms are integral membrane proteins expressed predominantly in the brain, although they are also present in other tissues. Neuroplastin is involved in various cellular processes, including cell adhesion, signal transduction, and calcium homeostasis. Its expression and function are essential for the proper formation and maintenance of synaptic connections, making it a key player in neurodevelopmental and neuropsychiatric disorders.
