Human Neuronal Apoptosis Inhibitory Protein (NAIP) Protein
Pida mas información
935106861
info@markelab.com
Precio
234€ (10 µg)
Protein NAIP
proveedor
Abbexareference
abx168706Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human NAIP Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
NLR Family Apoptosis Inhibitory Protein (NAIP) is a member of the NOD-like receptor (NLR) family involved in innate immunity and apoptosis regulation It plays a key role in forming the inflammasome, a multiprotein complex that activates caspase-1 leading to the maturation of IL-1β and IL-18 during immune responses NAIP recognizes bacterial flagellin and type III secretion system components triggering the activation of NLRC4 inflammasomes particularly in macrophages NAIP’s anti-apoptotic role is mediated through inhibition of caspase activity which helps protect cells during stress or infection Dysregulation of NAIP expression has been associated with neurodegenerative diseases such as spinal muscular atrophy (SMA) where deletions or mutations in the NAIP gene contribute to motor neuron degeneration Elevated levels of NAIP have also been observed in cancer cells where it aids in apoptosis resistance and tumor progression highlighting its dual role in survival and immune defense
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Neuronal Apoptosis Inhibitory Protein (NAIP)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 29.4 kDa Observed MW (SDS-PAGE): 29 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asn923-Val1148 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
NAIP
dry ice
No
availability
Shipped within 5-7 working days.
alias
Neuronal apoptosis inhibitory protein,Baculoviral IAP repeat-containing protein 1
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Human NAIP(Baculoviral IAP repeat-containing protein 1) ELISA Kit
proveedor
FineTestreference
EH1787reactivity
humanstatus
RUOPrecio a consultar
Ver másHuman Neuronal Apoptosis Inhibitory Protein (NAIP) ELISA Kit
proveedor
Abbexareference
abx054526Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Neuronal Apoptosis Inhibitory Protein (NAIP) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement o...
611€ (96 tests)
Ver másMouse Neuronal Apoptosis Inhibitory Protein (NAIP) Protein
proveedor
Abbexareference
abx068251Tested Applications
WB, SDS-PAGEstatus
RUORecombinant Neuronal Apoptosis Inhibitory Protein (NAIP) is a recombinant Mouse protein produced in a Prokaryotic expres...
221€ (10 µg)
Ver más