Name: Human Neuronal Apoptosis Inhibitory Protein (NAIP) ELISA Kit
Brand: Abbexa
SKU: abx251094
Price: 525 EUR
Availability: OnlineOnly

Background

NLR Family Apoptosis Inhibitory Protein (NAIP) is a member of the NOD-like receptor (NLR) family involved in innate immunity and apoptosis regulation It plays a key role in forming the inflammasome, a multiprotein complex that activates caspase-1 leading to the maturation of IL-1β and IL-18 during immune responses NAIP recognizes bacterial flagellin and type III secretion system components triggering the activation of NLRC4 inflammasomes particularly in macrophages NAIP’s anti-apoptotic role is mediated through inhibition of caspase activity which helps protect cells during stress or infection Dysregulation of NAIP expression has been associated with neurodegenerative diseases such as spinal muscular atrophy (SMA) where deletions or mutations in the NAIP gene contribute to motor neuron degeneration Elevated levels of NAIP have also been observed in cancer cells where it aids in apoptosis resistance and tumor progression highlighting its dual role in survival and immune defense

Características del producto

immunogen target

Neuronal Apoptosis Inhibitory Protein (NAIP)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

sensitivity

0.1 ng/ml

assay type

Sandwich

assay data

Quantitative

detection method

Colorimetric

sample type

Serum,Plasma,Other biological fluids

size 1

96 tests

alias

Neuronal apoptosis inhibitory protein,Baculoviral IAP repeat-containing protein 1

storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit

or code

NAIP

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q13075

note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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Human NAIP(Baculoviral IAP repeat-containing protein 1) ELISA Kit

proveedor

FineTest

reference

EH1787

reactivity

human

status

RUO

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