Human Neuromedin U receptor 1 (NMUR1) ELISA Kit

Este producto es parte de NMUR - Neuromedin U receptor
Human Neuromedin U receptor 1 (NMUR1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for NMUR1

proveedor

Abbexa

reference

abx381833

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Neuromedin U receptor 1 (NMUR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NMUR1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

NMUR1 is a G protein-coupled receptor activated by neuromedin U (NMU), a neuropeptide involved in regulating appetite, energy homeostasis, and inflammation. NMUR1 is primarily expressed in peripheral tissues, including the gastrointestinal tract, lungs, and immune cells, where it mediates NMU’s effects on smooth muscle contraction, inflammation, and immune responses. Upon activation, NMUR1 couples to Gq/11 proteins, leading to phospholipase C (PLC) activation, calcium mobilization, and smooth muscle contraction. NMUR1 plays a role in regulating gut motility, bronchoconstriction, and inflammatory responses, particularly in allergic conditions such as asthma and inflammatory bowel disease (IBD). Dysregulation of NMUR1 signaling contributes to inflammatory and metabolic disorders, where it amplifies immune responses and modulates energy expenditure. NMUR1 antagonists are being investigated for their potential to treat inflammatory diseases, asthma, and obesity, as NMU signaling through NMUR1 influences inflammation, energy balance, and smooth muscle activity.

Características del producto

category

ELISA Kits


immunogen target

Neuromedin U receptor 1 (NMUR1)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

NMUR1,FM-3,FM3,GPC-R,GPR66,NMU1R,SNORF62


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

NMUR1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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