Human Neurexin 3 (NRXN3) Protein (Active)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Human Neurexin-3-beta Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human NRXN3 isoform 2 (NP_620426.2) extracellular domain (Met 1-Thr 357) was fused with the Fc region of human IgG1 at the C-terminus.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Neurexin-3-beta |
| Host | HEK293 cells |
| Assay Type | Activity: Active Biological Activity: Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. When 5 × 104 cells/well are added to NRXN3 coated plates (0.8 µg/ml and 100 µl/well), >30% will adhere specifically after 1 hr at 37 °C. Sequence Fragment: Met1-Thr357 Tag: C-terminal Fc tag |
| Origin | Human |
| Observed MW | Calculated MW: 61.6 kDa Observed MW: 75 kDa, 85 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4, containing 15% trehalose. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | NP_620426.2 |
| Background | Protein NRXN3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. It is recommended to centrifuge the vial prior to use to bring the content to the bottom. Reconstitute in sterile H2O to prepare a stock solution of concentration 0.25 mg/ml. Do not vortex. Endotoxin Level: < 1.0 EU per µg as determined by the LAL method. |
Descripción
Related Products
Human NRXN3 (Neurexin-3) ELISA Kit
Ver Producto
Neurexin 3 (NRXN3) Antibody
Neurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of which two, NRXN1 and NRXN3, are among the largest known human genes. Three of the genes (NRXN1-3) utilize two alternate promoters and include numerous alternatively spliced exons to generate thousands of distinct mRNA transcripts and protein isoforms. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms; a much smaller number of transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. [provided by RefSeq].
Ver Producto