Human Neuregulin 4 (NRG4) CLIA Kit
845€ (96 tests)
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name
Human Neuregulin 4 (NRG4) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx493518
tested applications
CLIA
Description
Human Neuregulin 4 (NRG4) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Neuregulin 4 (NRG4) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.056 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8WWG1, Q0P6N4, Q0P6N5 |
| Alias | HRG4,Pro-NRG4,Pro-neuregulin-4 membrane-bound isoform |
| Background | CLIA Kits NRG4 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Neuregulin 4 (NRG4) is a member of the neuregulin family, which consists of growth factors that play critical roles in cell signaling, development, and homeostasis. NRG4 primarily acts through the ErbB family of receptor tyrosine kinases, notably interacting with ErbB4 to initiate downstream signaling pathways. This signaling is involved in a variety of physiological processes, including metabolism, tissue repair, and the regulation of energy balance. Research suggests that NRG4 may have protective roles in metabolic disorders, such as obesity and type 2 diabetes, by modulating insulin sensitivity and inflammatory responses in key tissues like the liver and adipose tissue. Additionally, NRG4's role in neuronal and cardiac development has also been noted, highlighting its importance across diverse biological systems. Further exploration of NRG4's signaling mechanisms may provide valuable insights into therapeutic strategies for metabolic and neurodegenerative diseases.
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