Human Neuregulin 3 (NRG3) Protein
208€ (10 µg)
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Name
Human Neuregulin 3 (NRG3) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx654503
Tested Applications
WB, SDS-PAGE
Description
Human Neuregulin 3 (NRG3) Protein is a recombinant Human protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Neuregulin 3 (NRG3) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Glu282-Pro342 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | HRG3,pro-NRG3,Pro-neuregulin-3 membrane-bound isoform |
| Background | Protein NRG3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
Neuregulin 3 (NRG3) is a specialized member of the neuregulin family, characterized by its expression in the central nervous system during key stages of brain development and throughout adulthood. It plays critical roles in cortical formation, neuronal migration, and the establishment of synaptic signaling networks. Acting through ErbB4 receptors, NRG3 is involved in shaping neural circuits that influence cognitive and behavioral functions. Variations in the NRG3 gene have been associated with psychiatric disorders such as schizophrenia and autism spectrum disorders. Its emerging importance in brain development and function makes it a valuable target for investigating neurological and psychiatric conditions, as well as for the development of innovative therapies.
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