Human Nerve Growth Factor Receptor (NGFR) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for NGFR
proveedor
Abbexareference
abx257284Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Nerve Growth Factor Receptor (NGFR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Nerve Growth Factor Receptor (NGFR) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
The nerve growth factor receptor (NGFR), also known as p75^NTR or CD271, is a receptor in the tumor necrosis factor receptor superfamily (TNFRSF) with critical roles in neuronal survival, differentiation, apoptosis, and regenerative processes. NGFR is primarily recognized for binding to nerve growth factor (NGF) but is also responsive to other neurotrophins, including brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). NGFR serves as a high-affinity receptor, particularly in conjunction with Trk receptors and sortilin, with functions ranging from promoting neuronal survival to facilitating apoptosis, depending on the cellular context and ligand interaction. NGFR has diverse roles beyond the nervous system, including in immune regulation, inflammatory responses, and tissue repair. In non-neuronal tissues, NGFR is involved in cell survival, migration, and differentiation. Due to its versatile functions, NGFR is implicated in neurodegenerative diseases, peripheral neuropathy, and various cancers, including melanoma and glioblastoma, where it often contributes to tumor progression and resistance to apoptosis.
Características del producto
category
ELISA Kits
immunogen target
Nerve Growth Factor Receptor (NGFR)
reactivity
Human
test range
78 pg/ml - 5000 pg/ml
sensitivity
< 35.6 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
Tumor necrosis factor receptor superfamily member 16,CD271,P75ntr,TNFRSF16,p75(NTR),Gp80-LNGFR,Low affinity neurotrophin receptor p75NTR
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
NGFR
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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