Human Nectin-4 (NECTIN4) Protein
312€ (20 µg)
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935106861
info@markelab.com
name
Human Nectin-4 (NECTIN4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694225
tested applications
SDS-PAGE
Description
Human Nectin-4 (NECTIN4) Protein is a recombinant Human protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Host | HEK293 cells |
| Origin | Human |
| Observed MW | Molecular Weight: Calculated MW: 38.28 kDa Observed MW (SDS-PAGE): 45 kDa Sequence Fragment: Met1-Ser349 Tag: C-terminal His tag |
| Expression | Recombinant |
| Purity | >95% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Form | Lyophilized Reconstitute in sterile H2O. Do not vortex. |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store lyophilized between -20 °C and -80 °C. |
| Dry Ice | No |
| UniProt ID | Q96NY8 |
| Gene ID | 8167 |
| Alias | LNIR,PRR4,EDSS1,PVRL4,nectin-4,Ig superfamily receptor LNIR,Nectin cell adhesion molecule 4,Poliovirus receptor-related protein 4 |
| Background | Protein NECTIN4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Nectin cell adhesion molecule 4 (NECTIN4) is highly expressed in epithelial tissues and has emerged as a significant player in cancer biology. Its overexpression is linked to the progression of aggressive cancers, including breast and urothelial carcinomas. NECTIN4 promotes tumor growth and metastasis by activating key signaling pathways such as PI3K/AKT and MAPK, which drive cell proliferation, survival, and migration. Its expression has also been associated with poor clinical outcomes, making it a potential biomarker and therapeutic target for cancer treatment strategies.
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