Human Natural Killer Cells Antigen CD94 (KLRD1) Protein

Este producto es parte de KLRD1 - killer cell lectin like receptor D1
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260€ (10 µg)

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935106861
info@markelab.com
name
Human Natural Killer Cells Antigen CD94 (KLRD1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067657
tested applications
WB, SDS-PAGE

Description

Recombinant Killer Cell Lectin Like Receptor Subfamily D, Member 1 (KLRD1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Natural Killer Cells Antigen CD94 (KLRD1)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 20.9 kDa  Observed MW (SDS-PAGE): 19 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Lys32-Ile179

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q13241
Alias
Natural killer cells antigen CD94,CD94,KP43,Killer cell lectin-like receptor subfamily D member 1,NK cell receptor
Background
Protein KLRD1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Killer Cell Lectin-Like Receptor D1 (KLRD1), commonly known as CD94, is a transmembrane protein that plays a crucial role in the immune system. Expressed on the surface of natural killer (NK) cells and certain subsets of T-cells, KLRD1 is primarily involved in recognizing and responding to infected or transformed cells. KLRD1 is part of the C-type lectin-like family of receptors, and its main function is to pair with other receptors (e.g., NKG2 family members) to mediate immune surveillance by recognizing peptide-loaded MHC class I molecules. Unlike other immune receptors that directly recognize pathogenic antigens, KLRD1 primarily regulates immune response through interaction with HLA-E, a non-classical MHC class I molecule presenting peptide sequences derived from other MHC class I molecules.

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KLRD1 Antibody is a Rabbit Polyclonal antibody against KLRD1. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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