Human Myosin Binding Protein C, Cardiac (MYBPC3) Protein
234€ (2 µg)
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name
Human Myosin Binding Protein C, Cardiac (MYBPC3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680540
tested applications
SDS-PAGE
Description
Human Myosin Binding Protein C, Cardiac (MYBPC3) Protein is a recombinant protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Myosin Binding Protein C, Cardiac (MYBPC3) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | FHC,CMH4,CMD1MM,LVNC10,MYBP-C,cMyBP-C,C-protein cardiac muscle isoform,Cardiac MyBP-C,Myosin-binding protein C, cardiac-type |
| Background | Protein MYBPC3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
MYBPC3 is a crucial component of the sarcomere in cardiac muscles, where it regulates cardiac contractility and stabilizes the structural framework of the thick filament. Through its interactions with myosin and actin, it modulates the force and efficiency of cardiac muscle contraction, playing a central role in maintaining the heart’s mechanical function. Mutations in MYBPC3 are a common genetic cause of hypertrophic cardiomyopathy (HCM), a condition characterized by the abnormal thickening of the heart muscle that can lead to heart failure and arrhythmias. These mutations often result in impaired sarcomere function and contribute to maladaptive cardiac remodeling. Research on MYBPC3 focuses on its role in cardiomyopathy pathogenesis and its potential as a therapeutic target for improving heart function in affected individuals.
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