Human Myosin Binding Protein C, Cardiac (MYBPC3) ELISA Kit
585€ (96 tests)
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name
Human Myosin Binding Protein C, Cardiac (MYBPC3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251905
tested applications
ELISA
Description
Human Myosin Binding Protein C, Cardiac (MYBPC3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Myosin Binding Protein C, Cardiac concentrations in serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Myosin Binding Protein C, Cardiac (MYBPC3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | 0.10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q14896 |
| Alias | FHC,CMH4,CMD1MM,LVNC10,MYBP-C,cMyBP-C,C-protein cardiac muscle isoform,Cardiac MyBP-C,Myosin-binding protein C, cardiac-type |
| Background | Elisa kits for MYBPC3 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
MYBPC3 is a crucial component of the sarcomere in cardiac muscles, where it regulates cardiac contractility and stabilizes the structural framework of the thick filament. Through its interactions with myosin and actin, it modulates the force and efficiency of cardiac muscle contraction, playing a central role in maintaining the heart’s mechanical function. Mutations in MYBPC3 are a common genetic cause of hypertrophic cardiomyopathy (HCM), a condition characterized by the abnormal thickening of the heart muscle that can lead to heart failure and arrhythmias. These mutations often result in impaired sarcomere function and contribute to maladaptive cardiac remodeling. Research on MYBPC3 focuses on its role in cardiomyopathy pathogenesis and its potential as a therapeutic target for improving heart function in affected individuals.
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