Human Mucin 1 (MUC1) CLIA Kit

Este producto es parte de MUC1 - mucin 1
Human Mucin 1 (MUC1) CLIA Kit

Pida mas información

935106861

info@markelab.com

Precio

845€ (96 tests)

CLIA Kits MUC1

proveedor

Abbexa

reference

abx491464

Tested Applications

CLIA

reactivity

Human

status

RUO

clonality

Descripción

Human Mucin 1/Krebs Von Den Lungen-6 (MUC1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.


Background

MUC1 (Mucin 1) is a large, transmembrane glycoprotein predominantly expressed on the surface of epithelial cells in various tissues, including the lungs, stomach, intestines, and the mammary glands. As a mucin protein, MUC1 plays a critical role in forming a protective mucous barrier on epithelial surfaces, which protects against environmental and microbial challenges. MUC1 also contributes to cell signaling and modulation of the immune response, particularly in epithelial cell inflammation. Due to its protective function on epithelial tissues, MUC1 expression is typically restricted to the apical surface of cells. However, in pathological states like cancer, MUC1 expression becomes dysregulated. Overexpression, aberrant glycosylation, and loss of polarity are commonly observed in many epithelial cancers, including breast, ovarian, and pancreatic cancers. These modifications contribute to tumor development, cancer cell survival, and metastasis, making MUC1 a key target for cancer diagnostics and therapeutics. In addition to cancer, MUC1 is associated with certain inflammatory and infectious diseases due to its role in the immune system.

Características del producto

category

CLIA Kits


immunogen target

Mucin 1 (MUC1)


reactivity

Human


test range

0.625 ng/ml - 40 ng/ml


sensitivity

< 0.25 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Chemiluminescent


sample type

Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

Cancer antigen 15-3,CA 15-3,EMA,MCD,PEM,PUM,KL-6,MAM6,MCKD,PEMT,CD227,H23AG,MCKD1,MUC-1,ADMCKD, ADTKD2,Ca15-3,MUC-1,Episialin


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

MUC1


dry ice

No


NCBI accession

NP_001018016.1, NM_001018016.2


note

The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Human MUC-1(Mucin-1) ELISA Kit

Human MUC-1(Mucin-1) ELISA Kit

proveedor

FineTest

reference

EH0406

reactivity

human

status

RUO

Precio a consultar

Ver más

Mouse MUC1(Mucin-1) ELISA Kit

Mouse MUC1(Mucin-1) ELISA Kit

proveedor

FineTest

reference

EM0387

reactivity

mouse

status

RUO

Precio a consultar

Ver más

anti- MUC1 antibody

anti- MUC1 antibody

proveedor

FineTest

reference

FNab05427

Tested Applications

ELISA, WB, FC, IHC, IP

reactivity

human

status

RUO

clonality

polyclonal

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a ...

Precio a consultar

Ver más