Human MRC2(C-type mannose receptor 2) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human MRC2(C-type mannose receptor 2) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH2106
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Size 1 | 96T |
| Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| UniProt ID | Q9UBG0 |
| Alias | C-type mannose receptor 2,CD280,UPARAP,CLEC13E,ENDO180,C-type lectin domain family 13 member E,Endocytic receptor 180,UPAR-associated protein |
| Background | Elisa Kits MRC2 |
| Status | RUO |
Mannose receptor C-type 2 (MRC2), also known as endocytic mannose receptor or uPARAP/Endo180, is a transmembrane glycoprotein receptor and a member of the C-type lectin family. MRC2 plays a significant role in the cellular processes of endocytosis and extracellular matrix (ECM) remodeling, particularly through binding and internalizing glycoproteins and matrix components. MRC2 is predominantly expressed in cells with endocytic functions, including fibroblasts, macrophages, and endothelial cells, and contributes to tissue homeostasis, immune response, and wound healing by modulating cellular uptake of glycosylated and collagenous materials. MRC2 is one of several mannose receptors, structurally distinct from others such as MRC1. Unlike MRC1, which is primarily involved in antigen capture and immune surveillance, MRC2 is most notable for its role in collagen uptake and degradation, positioning it as a unique player in matrix remodeling and turnover. The receptor's collagen-binding capacity has been linked to its role in tumor progression and metastasis in cancer as well as in fibrosis, where excessive ECM accumulation disrupts normal tissue function.
Related Products
Human MRC2(C-type mannose receptor 2) ELISA Kit
Ver Producto
anti- CD280 antibody
This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
Ver Producto
Mannose Receptor C Type 2 (MRC2) Antibody
Rabbit polyclonal antibody against MRC2 protein. Immunogen region is N-terminal.
Ver Producto