Human Mitogen-Activated Protein Kinase 8 (MAPK8) Protein
351€ (20 µg)
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935106861
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name
Human Mitogen-Activated Protein Kinase 8 (MAPK8) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx600135
tested applications
SDS-PAGE
Description
Human Mitogen-Activated Protein Kinase 8 (MAPK8) Protein is a recombinant full-length protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Mitogen-Activated Protein Kinase 8 (MAPK8) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: 1-427 AA Tag: C-terminal His tag |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 55.2 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Size 3 | 1 mg |
| Tested Applications | SDS-PAGE |
| Buffer | Tris/PBS based, containing 50% glycerol. |
| Availability | Shipped within 15-25 working days. |
| Storage | Aliquot and store at -20 °C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P45983 |
| Gene ID | 5599 |
| Background | Protein MAPK8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73, mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa.
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