Human Microfibrillar Associated Protein 4 (MFAP4) Protein

Este producto es parte de MFAP - microfibril associated protein
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208€ (10 µg)

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935106861
info@markelab.com
name
Human Microfibrillar Associated Protein 4 (MFAP4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690442
tested applications
SDS-PAGE

Description

Human Microfibril-Associated GlycoProtein is a recombinant protein from Human produced in Human Cells. Recombinant Human Microfibril-associated glycoprotein 4 is produced by our Mammalian expression system and the target gene encoding Val22-Ala255 is expressed with a 6His tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Microfibril-Associated GlycoProtein
Host
Human
Origin
Human
Observed MW
Molecular Weight: 27.5 kDa
Sequence Fragment: Val22-Ala255
Tag: C-terminal 6 His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Buffer
20mM PB, 150mM NaCl, pH7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
UniProt ID
P55083
Alias
MFAP4
Background
Protein MFAP4
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

MFAP4 is a glycoprotein that plays a key role in the structural organization and function of the extracellular matrix (ECM), particularly in tissues requiring elasticity such as blood vessels, lungs, and skin. It interacts with elastin and fibrillin-containing microfibrils to support elastic fiber assembly and stability, contributing to tissue elasticity and resilience. Beyond its structural role, MFAP4 has been implicated in mediating cellular adhesion and interactions with integrins, influencing cell migration and repair processes. Additionally, MFAP4 is being explored as a biomarker for various diseases, including fibrotic disorders, cardiovascular conditions, and liver fibrosis. Current research continues to elucidate its involvement in ECM-related pathologies and its potential as a therapeutic target for diseases linked to compromised ECM integrity.

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