Human Microfibrillar Associated Protein 4 (MFAP4) Protein
208€ (10 µg)
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name
Human Microfibrillar Associated Protein 4 (MFAP4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690442
tested applications
SDS-PAGE
Description
Human Microfibril-Associated GlycoProtein is a recombinant protein from Human produced in Human Cells. Recombinant Human Microfibril-associated glycoprotein 4 is produced by our Mammalian expression system and the target gene encoding Val22-Ala255 is expressed with a 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Microfibril-Associated GlycoProtein |
| Host | Human |
| Origin | Human |
| Observed MW | Molecular Weight: 27.5 kDa Sequence Fragment: Val22-Ala255 Tag: C-terminal 6 His tag |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM PB, 150mM NaCl, pH7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | P55083 |
| Alias | MFAP4 |
| Background | Protein MFAP4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
MFAP4 is a glycoprotein that plays a key role in the structural organization and function of the extracellular matrix (ECM), particularly in tissues requiring elasticity such as blood vessels, lungs, and skin. It interacts with elastin and fibrillin-containing microfibrils to support elastic fiber assembly and stability, contributing to tissue elasticity and resilience. Beyond its structural role, MFAP4 has been implicated in mediating cellular adhesion and interactions with integrins, influencing cell migration and repair processes. Additionally, MFAP4 is being explored as a biomarker for various diseases, including fibrotic disorders, cardiovascular conditions, and liver fibrosis. Current research continues to elucidate its involvement in ECM-related pathologies and its potential as a therapeutic target for diseases linked to compromised ECM integrity.
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