Human Microfibrillar Associated Protein 4 (MFAP4) Protein
234€ (10 µg)
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name
Human Microfibrillar Associated Protein 4 (MFAP4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166122
tested applications
WB, SDS-PAGE
Description
Microfibrillar Associated Protein 4 is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Microfibrillar Associated Protein 4 (MFAP4) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 30.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val22-Ala255 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | MFAP4 |
| Background | Protein MFAP4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
MFAP4 is a glycoprotein that plays a key role in the structural organization and function of the extracellular matrix (ECM), particularly in tissues requiring elasticity such as blood vessels, lungs, and skin. It interacts with elastin and fibrillin-containing microfibrils to support elastic fiber assembly and stability, contributing to tissue elasticity and resilience. Beyond its structural role, MFAP4 has been implicated in mediating cellular adhesion and interactions with integrins, influencing cell migration and repair processes. Additionally, MFAP4 is being explored as a biomarker for various diseases, including fibrotic disorders, cardiovascular conditions, and liver fibrosis. Current research continues to elucidate its involvement in ECM-related pathologies and its potential as a therapeutic target for diseases linked to compromised ECM integrity.
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