Human Melanocortin 5 Receptor (MC5R) CLIA Kit
845€ (96 tests)
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935106861
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name
Human Melanocortin 5 Receptor (MC5R) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx190392
tested applications
CLIA
Description
Human Melanocortin 5 Receptor (MC5R) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Melanocortin 5 Receptor (MC5R) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 13.7 pg/ml - 10000 pg/ml |
| Sensitivity | < 5.5 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | MC5R,MC2,melanocortin receptor 5 |
| Background | CLIA Kits MC5R |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
MC5R is a G protein-coupled receptor activated by melanocortins, including α-MSH and ACTH. It is widely expressed in various peripheral tissues, including the skin, adrenal glands, and exocrine glands. MC5R regulates the production of sebaceous lipids in sebaceous glands, contributing to skin and hair lubrication and barrier function. It also influences inflammatory responses, immune regulation, and steroidogenesis. In immune cells, MC5R activation suppresses pro-inflammatory cytokine production, highlighting its role in anti-inflammatory processes. Dysregulation of MC5R has been implicated in skin disorders such as acne, where altered lipid production disrupts skin homeostasis. MC5R may also play a role in regulating energy metabolism, muscle growth, and thermogenesis. Therapeutically, MC5R agonists are being explored for their potential in treating inflammatory skin conditions, metabolic dysfunction, and immune-related disorders. Its diverse roles in lipid production, inflammation, and tissue homeostasis make MC5R a promising target for skin and metabolic therapies.
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