Human MCM6 (minichromosome maintenance complex component 6) QuickTest ELISA Kit

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Product specifications
Category | ELISA Kits |
Reactivity | Human |
Assay Data | 120 minutes |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 46.875-3000pg/ml |
Sensitivity | 28.125pg/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, plasma, cell culture supernatant, cell lysate or tissue lysate, other biological fluid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | Q14566 |
Alias | DNA replication licensing factor MCM6, p105MCM, MCM6 |
Background | Elisa kits for MCM6 |
Status | RUO |
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Human MCM6 (minichromosome maintenance complex component 6) ELISA Kit
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MCM6 antibody
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.
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