Human MC5R (Melanocortin receptor 5) ELISA Kit

Este producto es parte de MC - Melanocortin Receptor
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935106861
info@markelab.com
name
Human MC5R (Melanocortin receptor 5) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH2369
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.781-50ng/ml
Sensitivity
0.469ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P33032
Alias
MC5R,MC2,melanocortin receptor 5
Background
Elisa kits for MC5R
Status
RUO

MC5R is a G protein-coupled receptor activated by melanocortins, including α-MSH and ACTH. It is widely expressed in various peripheral tissues, including the skin, adrenal glands, and exocrine glands. MC5R regulates the production of sebaceous lipids in sebaceous glands, contributing to skin and hair lubrication and barrier function. It also influences inflammatory responses, immune regulation, and steroidogenesis. In immune cells, MC5R activation suppresses pro-inflammatory cytokine production, highlighting its role in anti-inflammatory processes. Dysregulation of MC5R has been implicated in skin disorders such as acne, where altered lipid production disrupts skin homeostasis. MC5R may also play a role in regulating energy metabolism, muscle growth, and thermogenesis. Therapeutically, MC5R agonists are being explored for their potential in treating inflammatory skin conditions, metabolic dysfunction, and immune-related disorders. Its diverse roles in lipid production, inflammation, and tissue homeostasis make MC5R a promising target for skin and metabolic therapies.

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