Human Mannose Receptor C Type 2 (MRC2) CLIA Kit
845€ (96 tests)
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name
Human Mannose Receptor C Type 2 (MRC2) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx491953
tested applications
CLIA
Description
Human Mannose Receptor C Type 2 (MRC2) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Mannose Receptor C Type 2 (MRC2) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.117 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | C-type mannose receptor 2,CD280,UPARAP,CLEC13E,ENDO180,C-type lectin domain family 13 member E,Endocytic receptor 180,UPAR-associated protein |
| Background | CLIA Kits MRC2 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Mannose receptor C-type 2 (MRC2), also known as endocytic mannose receptor or uPARAP/Endo180, is a transmembrane glycoprotein receptor and a member of the C-type lectin family. MRC2 plays a significant role in the cellular processes of endocytosis and extracellular matrix (ECM) remodeling, particularly through binding and internalizing glycoproteins and matrix components. MRC2 is predominantly expressed in cells with endocytic functions, including fibroblasts, macrophages, and endothelial cells, and contributes to tissue homeostasis, immune response, and wound healing by modulating cellular uptake of glycosylated and collagenous materials. MRC2 is one of several mannose receptors, structurally distinct from others such as MRC1. Unlike MRC1, which is primarily involved in antigen capture and immune surveillance, MRC2 is most notable for its role in collagen uptake and degradation, positioning it as a unique player in matrix remodeling and turnover. The receptor's collagen-binding capacity has been linked to its role in tumor progression and metastasis in cancer as well as in fibrosis, where excessive ECM accumulation disrupts normal tissue function.
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