Human Macrophage Mannose Receptor 1 (MRC1) ELISA Kit

Este producto es parte de MRC1 - mannose receptor C-type 1
Product Graph
689€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Macrophage Mannose Receptor 1 (MRC1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx572570
tested applications
ELISA

Description

Human Macrophage Mannose Receptor 1 (MRC1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Macrophage Mannose Receptor 1 (MRC1) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Mannose Receptor C Type 1 (MRC1)

Documents del producto

Instrucciones
Descargar
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Macrophage Mannose Receptor 1 (MRC1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.13 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P22897
Gene ID
4360
NCBI Accession
NP_002429.1
OMIM
153618
Alias
Macrophage mannose receptor 1,MMR,hMR,CD206,MRC1L1,CLEC13D; CLEC13DL,C-type lectin domain family 13 member D,C-type lectin domain family 13 member D-like,Macrophage mannose receptor 1-like protein 1
Background
Elisa kits for MRC1
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

MRC1, or mannose receptor C-type 1, is a type I transmembrane protein predominantly found on the surface of macrophages, dendritic cells, and certain endothelial cells. The receptor, encoded by the MRC1 gene, plays an essential role in immune surveillance and host defense against pathogens. It is a member of the C-type lectin receptor (CLR) family, a group of proteins involved in recognizing carbohydrate structures on pathogens, facilitating their capture, and subsequently initiating immune responses. The mannose receptor (MR) recognizes and binds to mannose, fucose, and N-acetylglucosamine residues, which are common on the surface of microorganisms, thereby enabling the immune system to detect a broad range of pathogens, including bacteria, fungi, and viruses. This recognition mechanism is crucial for identifying foreign pathogens that display distinct glycosylation patterns on their surfaces compared to host cells. Beyond its role in pathogen recognition, MRC1 is involved in various physiological processes, including antigen processing and presentation, phagocytosis, and homeostasis. By mediating endocytosis of specific ligands and facilitating the clearance of glycoproteins and degraded cell components, MRC1 supports tissue repair and cellular turnover, making it integral to both innate immunity and tissue remodeling.

Related Products

EH1802

Human MRC1 (Macrophage mannose receptor 1) ELISA Kit

Ver Producto
P0523

Recombinant Human MRC1

Ver Producto
QT-EH1802

Human MRC1 (Macrophage mannose receptor 1) QuickTest ELISA Kit

Ver Producto