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Human Lymphocyte Function Associated Antigen 3 / LFA-3 (CD58) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
562.5€ (96 tests)
Elisa Kits CD58
proveedor
Abbexareference
abx250326Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Lymphocyte Function Associated Antigen 3 / LFA-3 (CD58) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Lymphocyte Function Associated Antigen 3 / LFA-3 (CD58) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CD58, also known as Lymphocyte Function-associated Antigen 3 (LFA-3), is a cell surface glycoprotein primarily involved in cell adhesion processes. It plays a critical role in the immune response by mediating the interaction between T cells and antigen-presenting cells (APCs). The CD58 protein is a member of the immunoglobulin (Ig) superfamily and is widely expressed on a variety of cell types, including epithelial cells, endothelial cells, lymphocytes, and dendritic cells. Its main binding partner is CD2, a receptor found on T cells and natural killer (NK) cells. This interaction is essential for the formation of the immune synapse, facilitating the activation of T cells and subsequent immune responses. CD58’s role is especially important in antigen presentation, where it helps T cells to recognize and respond to foreign antigens. The molecule is involved in co-stimulation during T-cell receptor (TCR) engagement, enhancing the immune system's ability to respond to pathogens, tumors, and other immunological challenges.
Características del producto
category
ELISA Kits
immunogen target
Lymphocyte Function Associated Antigen 3 / LFA-3 (CD58)
reactivity
Human
test range
12.5 pg/ml - 800 pg/ml
sensitivity
7.5 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
ag3,LFA3,LFA-3,Lymphocyte function-associated antigen 3,Surface glycoprotein LFA-3
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
CD58
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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