Human Lymphocyte antigen 75 (LY75) ELISA Kit

Product specifications

ELISA Kits

Lymphocyte antigen 75 (LY75)

Human

Colorimetric

Quantitative

0.156 ng/ml - 10 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

ELISA

Tissue homogenates, cell lysates and other biological fluids.

Shipped within 5-15 working days. The validity for this kit is 6 months.

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

O60449

604524

C-type lectin domain family 13 member B,CD205,LY-75,CLEC13B,DEC-205,GP200-MR6,Lymphocyte antigen 75

Elisa kits for LY75

RUO

Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

LY75, also known as lymphocyte antigen 75, is a protein primarily involved in the immune system, specifically in antigen processing and presentation. LY75 is also referred to as DEC-205 (dendritic and epithelial cell 205) and is encoded by the LY75 gene in humans. LY75 belongs to the C-type lectin receptor family, which includes proteins involved in recognizing carbohydrate structures on pathogens, facilitating immune cell recognition, and initiating immune responses. It is a type I transmembrane protein highly expressed in dendritic cells (DCs), especially in lymphoid tissues, and also found on certain types of epithelial cells. Through its antigen-capturing ability, LY75 has a significant role in promoting immune tolerance and in the activation of T cells. LY75 functions as a receptor that binds to specific antigens, internalizes them, and processes them for presentation on major histocompatibility complex (MHC) molecules, primarily MHC class II. This makes it a critical component in activating adaptive immune responses, especially against infections, tumors, and other immune challenges. The ability of LY75 to capture and process antigens, combined with its expression pattern, positions it as an important target for immunotherapy, especially in contexts where modulation of the immune response, such as cancer immunotherapy and vaccine development, is desired.

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