Human LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3) ELISA Kit

Este producto es parte de LIMS - LIM zinc finger domain containing
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715€ (96 tests)

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935106861
info@markelab.com
name
Human LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531036
tested applications
ELISA

Description

Human LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P0CW19
Alias
LIMS3L, LIMS4, PINCH-3,LIM and senescent cell antigen-like-containing domain protein 3
Background
Elisa kits for LIMS3
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

LIMS3 is a member of the LIM-domain-containing protein family, though it is less well-characterized compared to LIMS1 and LIMS2. It is believed to play a role in focal adhesion dynamics, cytoskeletal organization, and integrin-mediated signaling. LIMS3 contains LIM domains that facilitate protein-protein interactions, potentially linking it to actin cytoskeleton remodeling and cellular adhesion processes. Its expression appears to be tissue-specific, with enrichment in skeletal muscle, cardiac tissue, and certain epithelial cells. While the exact biological functions remain unclear, emerging evidence suggests LIMS3 may contribute to mechanical stress responses, tissue remodeling, and cell migration. Dysregulation of LIMS3 is associated with structural tissue defects and may play a role in tumor progression and metastasis. Functional studies are needed to define its precise roles in integrin signaling, cellular adhesion, and tissue-specific development.

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