Human Leukosialin (SPN) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for SPN
proveedor
Abbexareference
abx251245Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Leukosialin (SPN) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leukosialin (SPN) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Sialophorin (SPN), also known as CD43, is a glycoprotein primarily expressed on the surface of immune cells, such as T lymphocytes, monocytes, neutrophils, and some B cells. SPN is involved in various aspects of immune cell function, including cell adhesion, migration, and activation. The molecule plays a critical role in modulating the interaction between immune cells and their microenvironment, particularly by regulating the adhesion properties of leukocytes, which are essential for their migration and trafficking through different tissues. Sialophorin is a highly sialylated protein, meaning it has many sialic acid residues attached to its extracellular portion, which contribute to its negative charge. This negative charge facilitates electrostatic repulsion between cells, which can prevent adhesion in certain contexts but also enables its participation in finely tuned immune responses. SPN is an important player in the immune system's ability to differentiate between self and non-self, contributing to immune surveillance and cellular interactions during inflammatory responses.
Características del producto
category
ELISA Kits
immunogen target
Leukosialin (SPN)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
LSN,CD43,GALGP,GPL115,LEU-22,Leukosialin, Galactoglycoprotein,Leukocyte sialoglycoprotein,Sialophorin
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
SPN
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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