Human Leukocyte surface antigen CD53 (CD53) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Human Leukocyte surface antigen CD53 (CD53) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx505793
tested applications
ELISA
Description
Human Leukocyte surface antigen CD53 (CD53) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leukocyte surface antigen CD53 (CD53) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
Category | ELISA Kits |
Immunogen Target | Leukocyte surface antigen CD53 (CD53) |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Test Range | 0.312 ng/ml - 20 ng/ml |
Sensitivity | < 0.13 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Size 2 | 5 × 96 tests |
Size 3 | 10 × 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | P19397 |
Gene ID | 963 |
OMIM | 151525 |
Alias | MOX44,TSPAN25,Leukocyte surface antigen CD53,Cell surface glycoprotein CD53,Tetraspanin-25 |
Background | Elisa kits for CD53 |
Status | RUO |
Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CD53 is a cell surface glycoprotein and a member of the tetraspanin superfamily, which plays a critical role in immune cell function. It is expressed primarily on hematopoietic cells, including leukocytes such as T cells, B cells, monocytes, neutrophils, and natural killer (NK) cells. CD53 is involved in immune cell signaling, adhesion, and trafficking, making it an important molecule for maintaining immune system integrity and function. CD53's role in facilitating interactions between immune cells and in transducing signals that promote activation and differentiation makes it a key participant in the regulation of immune responses. The tetraspanins, of which CD53 is a member, are integral membrane proteins that form complexes with other membrane proteins, including integrins, growth factor receptors, and immune receptors. CD53 is known to associate with other tetraspanins and create specialized membrane domains called tetraspanin-enriched microdomains (TEMs), which function in organizing membrane proteins and coordinating signaling pathways. The protein has been implicated in the immune system’s defense against pathogens and in the activation and function of leukocytes.
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