Human Leukocyte Immunoglobulin Like Receptor Subfamily A Member 3 (LILRA3) Protein

Este producto es parte de LILRA3 - leukocyte immunoglobulin like receptor A3
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429€ (20 µg)

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935106861
info@markelab.com
name
Human Leukocyte Immunoglobulin Like Receptor Subfamily A Member 3 (LILRA3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691434
tested applications
SDS-PAGE

Description

Human ILT6 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human LILRA3 (AAH28208.1) (Met1-Glu439) was expressed with a polyhistidine tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
ILT6
Host
HEK293 cells
Origin
Human
Observed MW
Molecular Weight: 46.5 kDa
Sequence Fragment: Met1-Glu439
Tag: C-terminal His tag
Validity: The validity for this protein is 12 months.
Expression
Recombinant
Purity
> 85% (SDS-PAGE)
Size 1
20 µg
Size 2
100 µg
Form
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
AAH28208.1
Alias
Leukocyte immunoglobulin-like receptor subfamily A member 3,HM31,HM43,ILT6,LIR4,CD85E,ILT-6,LIR-4,Immunoglobulin-like transcript 6,Leukocyte immunoglobulin-like receptor 4,Monocyte inhibitory receptor HM43/HM31
Background
Protein LILRA3
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

LILRA3 (Leukocyte Immunoglobulin-Like Receptor A3), also referred to as ILT6 or CD85e, is an intriguing member of the leukocyte immunoglobulin-like receptor (LILR) family, which is predominantly expressed on immune cells. LILRA3 is unique among LILR family members because it lacks a transmembrane domain, functioning as a soluble molecule. Found within the Leukocyte Receptor Complex (LRC) on chromosome 19q13.4, LILRA3 plays a significant role in modulating immune responses, particularly in inflammatory pathways. As a soluble receptor, LILRA3 is capable of binding various ligands, which include MHC class I molecules, and thus can modulate signaling pathways related to immune tolerance and immune response activation. Its specific function in the immune system remains somewhat enigmatic, as both pro-inflammatory and inhibitory effects have been suggested. However, it is recognized as a key player in regulating inflammation and immune homeostasis, with particular relevance in autoimmune diseases, infections, and certain cancers
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